Chlojaponilactone B

Overview

Chlojaponilactone B is a lindenane-type sesquiterpenoid with anti-inflammatory properties. Chlojaponilactone B suppresses inflammatory responses by inhibiting TLR4 and subsequently decreasing reactive oxygen species (ROS) generation, downregulating the NF-κB , thus reducing the expression of the pro-inflammatory cytokines iNOS , NO, COX-2 , IL-6 and TNF-α.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Toll-like Receptor (TLR) | Products > Signaling Pathways > Reactive Oxygen Species (ROS) | Products > Signaling Pathways > NF-κB

Product Information

• Catalog No.: HY-N8413
• CAS No.: 1449382-91-5
• Molecular Formula: C17H18O4
• Molecular Weight: 286.32
• Purity: 98.0%
• Storage: -20°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Availability: In-stock

Source

Original product source