Itriglumide (CR 2945) is an anthranilic acid derivative. Itriglumide is a potent and selective CCKB receptor antagonist, with an IC 50 of 2.3 nM. Itriglumide antagonizes the response to gastrin in a dose-dependent manner with an IC 50 of 5.9 nM. Itriglumide shows antisecretory and antiulcer activity.
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Cholecystokinin Receptor
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