Umckalin is Coumarin ( HY-N0709 ) derivative that exhibits anti-inflammatory properties. Umckalin reduces phosphorylation of p38 MAPK , JNK , and ERK , lowers TNF-α , IL-6 , IL-1β , NO, and PGE 2 production. Umckalin can be used for the research of chronic inflammatory diseases.
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > TNF Receptor | Products > Signaling Pathways > Interleukin Related | Products > Signaling Pathways > PI3K | Products > Signaling Pathways > Akt | Products > Signaling Pathways > p38 MAPK | Products > Signaling Pathways > JNK | Products > Signaling Pathways > ERK
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