Nebicapone

Overview

Nebicapone (BIA 3-202), a reversible catechol-O-methyltransferase ( COMT ) inhibitor, is mainly metabolized by glucuronidation. Nebicapone is mainly peripherally acting inhibitor that decreases the biotransformation of L-DOPA to 3-O-methyl-DOPA by inhibition of COMT , and it is potential for the treatment of Parkinson's disease.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Neurodegenerative Disease | Products > Disease Areas > Parkinson's Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > COMT

Product Information

• Catalog No.: HY-106405
• CAS No.: 274925-86-9
• Molecular Formula: C14H11NO5
• Molecular Weight: 273.24
• Purity: 99.89%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: ≥ 2.5 mg/mL (9.15 mM); Clear solution
• Availability: In-stock

Source

Original product source