DPLG3 is a specific chymotryptic-like β5i subunits inhibitor, with an IC 50 of 4.5 nM. DPLG3 inhibits mouse i-20S with IC 50 of 9.4 nM. DPLG3 downregulates the protein levels of NF-κB p50 and p65 . DPLG3 can be used for immune disease research .
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