Xelafaslatide

Overview

Xelafaslatide (ONL-1204) is a Fas receptor antagonist. Xelafaslatide blocks the Fas receptor signaling pathway and inhibits downstream apoptosis and inflammatory pathways. Xelafaslatide suppresses neuroinflammation and microglial activation in glaucoma models, protects retinal ganglion cells and prevents axonal degeneration. Xelafaslatide is applicable to relevant research on glaucoma.

Application

Products | Products > Peptides | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Visual System Disease | Products > Disease Areas > Glaucoma | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Caspase | Products > Signaling Pathways > Fatty Acid Synthase (FASN) | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Interleukin Related | Products > Signaling Pathways > Toll-like Receptor (TLR) | Products > Signaling Pathways > NOD-like Receptor (NLR)

Product Information

• Catalog No.: HY-P10227
• CAS No.: 2040964-58-5
• Molecular Formula: C71H100N18O16
• Molecular Weight: 1461.66
• Purity: 99.88%
• Storage: Sealed storage, away from moisture. Powder -80°C, 2 years , -20°C, 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 2.5 mg/mL (1.71 mM); Clear solution
• Availability: In-stock

Source

Original product source