EPI-X4

Overview

EPI-X4 (hSA408–423 peptide) is an antagonist for C-X-C motif chemokine receptor 4 ( CXCR4 ) with IC 50 of 8.6 μM. EPI-X4 blocks the CXCL12-mediated signaling, inhibits chemokine-mediated migration and invasion of leukemia cell. EPI-X4 exhibits anti-inflammatory activity in mouse model. EPI-X4 exhibits antiviral activity against CXCR4-tropic HIV with IC 50 of 8.6 μM.

Application

Products | Products > Peptides | Products > Disease Areas > Cancer | Products > Disease Areas > Infection | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Infection | Products > Signaling Pathways > CXCR

Product Information

• Catalog No.: HY-P10415
• CAS No.: 930280-31-2
• Molecular Formula: C84H144N22O23
• Molecular Weight: 1830.18
• Purity: 98.91%
• Storage: Sealed storage, away from moisture. Powder -80°C, 2 years , -20°C, 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 2.5 mg/mL (1.37 mM); Clear solution
• Availability: In-stock

Source

Original product source