TAT-PiET is a cell-penetrating peptide targeting the extra-terminal (ET) domain of BRD4 . TAT-PiET can reduce BRD4 and JMJD6 levels and inhibit cell proliferation. TAT-PiET also resists the endocrine resistance of ERα-positive breast cancer cells. TAT-PiET can be used for the research of cancer , such as breast cancer .
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