[Leu144,Arg147]-PLP (139-151)

Overview

[Leu144,Arg147]-PLP (139-151) is a mutant peptide fragment of myelin proteolipid protein (PLP), with the tryptophan and histidine at positions 144 and 147 respectively replaced by leucine and arginine. [Leu144,Arg147]-PLP (139-151) also serves as a T cell receptor ( TCR ) antagonist for encephalitogenic Th1 clones, blocking their activation in vitro . Furthermore, [Leu144,Arg147]-PLP (139-151) can inhibit the development of experimental autoimmune encephalomyelitis (EAE).

Application

Products | Products > Peptides | Products > Disease Areas > Inflammation or Immune System Disease | Products > Research Areas > Inflammation/Immunology

Product Information

• Catalog No.: HY-P10456
• CAS No.: 188859-65-6
• Molecular Formula: C67H110N20O17
• Molecular Weight: 1467.71
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source