LXY3

Overview

LXY3 (LXY2) is a VLA-3 -blocking peptide that inhibits the interaction between integrin α3β1 ( VLA-3 ) on neutrophil surfaces and laminin in the basement membrane, thereby preventing neutrophil migration across the tumor vascular basement membrane barrier. LXY3 is used to block neutrophil-mediated nanoparticle release from perivascular pools into the tumor interstitium. LXY3 is commonly employed for targeted imaging of breast cancer .

Application

Products | Products > Peptides | Products > Signaling Pathways > Cytoskeleton | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Integrin

Product Information

• Catalog No.: HY-P10934
• CAS No.: 1095009-44-1
• Molecular Formula: C32H43N11O15S2
• Molecular Weight: 885.88
• Purity: 98.33%
• Storage: Sealed storage, away from moisture. Powder -80°C, 2 years , -20°C, 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Availability: In-stock

Source

Original product source