LNSMGQD

Overview

LNSMGQD is a cyclic peptide fragment derived from desmoglein 1 ( amino acids 81-86), which mimics trans-interactions and acts as part of the tandem peptide binding interface of desmoglein 2. LNSMGQD not only binds to desmoglein 1 and 3, but also effectively inhibits their homophilic trans-interactions, while reducing the probability of homophilic or heterophilic binding between desmoglein 2 and Dsc2, N-cadherin and E-cadherin . LNSMGQD is applicable to the research on disease mechanisms such as Crohn's disease and pemphigus vulgaris.

Application

Products | Products > Peptides | Products > Disease Areas > Crohn's Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Autoimmune Disease | Products > Disease Areas > Digestive System Inflammation | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > Cytoskeleton | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > p38 MAPK | Products > Signaling Pathways > Cadherin

Product Information

• Catalog No.: HY-P11017
• CAS No.: 1152066-26-6
• Molecular Formula: C29H49N9O13S
• Molecular Weight: 763.82
• Purity: 99.92%
• Storage: Sealed storage, away from moisture. Powder -80°C, 2 years , -20°C, 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Availability: In-stock

Source

Original product source