Davalintide

Overview

Davalintide is an Amylin ( HY-P1464 )-mimetic peptide with greater potency and longer-lasting effects. Davalintide is a potent agonist of amylin receptor ( IC 50 = 0.04 nM), calcitonin receptor ( IC 50 = 0.06 nM) and calcitonin related peptide receptor ( CGRP receptor ) ( IC 50 = 3.1 nM). Davalintide shows stronger potency to Amylin to activate cyclic AMP production through the calcitonin receptor ( EC 50 = 1.4 nM). Davalintide regulates blood sugar and weight through various mechanisms such as delaying gastric emptying, inhibiting glucagon secretion, and reducing food intake. Davalintide can be used for the studies of anti-obesity and anti-diabetes.

Application

Products | Products > Peptides | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Amylin Receptor | Products > Signaling Pathways > CGRP Receptor

Product Information

• Catalog No.: HY-P11320
• CAS No.: 863919-85-1
• Molecular Formula: C152H248N50O49S2
• Molecular Weight: 3624.03
• Purity: 98.04%
• Storage: Sealed storage, away from moisture. Powder -80°C, 2 years , -20°C, 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Availability: In-stock

Source

Original product source