Cyclotraxin B

Overview

Cyclotraxin B is a BBB-penetrable and selective TrkB inhibitor. Cyclotraxin B inhibits BDNF-induced TrkB activity in a non-competitive manner, with an IC 50 of 0.30 nM. Cyclotraxin B has analgesic and anxiolytic effects.

Application

Products | Products > Peptides | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Trk Receptor | Products > Signaling Pathways > p38 MAPK

Product Information

• Catalog No.: HY-P1178
• CAS No.: 1203586-72-4
• Molecular Formula: C48H73N13O17S3
• Molecular Weight: 1200.37
• Purity: 99.78%
• Storage: Stored under nitrogen, away from moisture. Powder -80°C, 2 years , -20°C, 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)
• Solubility: 100 mg/mL (83.31 mM); Clear solution; Need ultrasonic
• Availability: In-stock

Source

Original product source