(D-Pro7)-Angiotensin I/II (1-7)

Overview

(D-Pro7)-Angiotensin I/II (1-7) is a potent Mas receptor inhibitor with a K i of 0.001 μM for rat receptors. (D-Pro7)-Angiotensin I/II (1-7) competitively blocks the binding of Angiotensin-(1-7) to the Mas receptor and attenuates the vasodilatory effect of rat aortas under physiological and hypertensive conditions. (D-Pro7)-Angiotensin I/II (1-7) can be used for studies on the function of the renin-angiotensin system and the pathological mechanisms of hypertension.

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Cardiovascular Disease | Products > Disease Areas > Hypertension | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Angiotensin Receptor | Products > Signaling Pathways > Mas-related G-protein-coupled Receptor (MRGPR)

Product Information

• Catalog No.: HY-P1656
• CAS No.: 586962-44-9
• Molecular Formula: C41H62N12O11
• Molecular Weight: 899.00
• Purity: 99.95%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: 1 mg/mL (1.11 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source