TAK-683

Overview

TAK-683 is a potent full KISS1 receptor (KISS1R) agonist ( IC 50 =170 pM) with improved metabolic stability. TAK-683 is a nonapeptide metastin analog, exhibits agonistic activities to KISS1R with EC 50 values of 0.96 nM and 1.6 nM for human and rat, respectively. TAK-683 depletes GnRH in the hypothalamus and reduces plasma FSH , LH, and testosterone levels in vivo, it has the potential for the study of hormone-dependent prostate cancer .

Application

Products | Products > Peptides | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Kisspeptin Receptor

Product Information

• Catalog No.: HY-P2161
• CAS No.: 872719-49-8
• Molecular Formula: C64H83N17O13
• Molecular Weight: 1298.45
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source