Competence-Stimulating Peptide-2 (CSP-2) is a 17-amino acid signal peptide produced by Streptococcus pneumoniae , with an EC 50 of 50.7 nM for its compatible receptor ComD2 . Competence-Stimulating Peptide-2 (CSP-2) can regulate bacterial phenotypes such as competence development, virulence, and biofilm formation through quorum sensing.
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