Urocortin II, mouse

Overview

Urocortin II, mouse is a potent and selective endogenous peptide agonist of type-2 corticotropin-releasing factor (CRF2) receptor with K i values of 0.66 nM and ﹥100 nM for CRFR2 and CRFR1 , respectively. Urocortin II, mouse activates CRF2 receptors in a cAMP/PKA- and Ca 2+ /CaMKII-dependent manner.Urocortin II, mouse is expressed in discrete areas of the central nervous system, and activates central neurons involved in the processing of visceral sensory information, and in modulating autonomic outflow.

Application

Products | Products > Peptides | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Metabolic Disease | Products > Research Areas > Endocrinology | Products > Signaling Pathways > CRFR

Product Information

• Catalog No.: HY-P2847
• CAS No.: 330648-32-3
• Molecular Formula: C187H320N56O50
• Molecular Weight: 4152.96
• Purity: 99.94%
• Storage: Sealed storage, away from moisture. Powder -80°C, 2 years , -20°C, 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Availability: In-stock

Source

Original product source