Cereulide- 13 C 6

Overview

Cereulide- 13 C 6 is a deuterated form of Cereulide. Cereulide is an orally active, blood-brain barrier-permeable emetic toxin. Cereulide acts as a potassium ionophore that inserts into membranes, forms complexes with K + , and transports K + from the cytoplasm into the mitochondrial matrix. Cereulide disrupts the electrochemical gradient of the inner mitochondrial membrane, leading to mitochondrial swelling and dysfunction, uncoupling of oxidative phosphorylation , inhibition of ATP synthesis, ROS accumulation, and ultimately triggering apoptosis and autophagy . Cereulide exhibits multi-organ toxicity and can be used for research on emetic food poisoning.

Application

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Product Information

• Catalog No.: HY-P3003S
• CAS No.: 1487375-69-8
• Molecular Formula: C5113C6H96N6O18
• Molecular Weight: 1159.36
• Purity: 97%
• Storage: Solution, -20°C, 2 years
• Availability: In-stock

Source

Original product source