NH2-c[X-R-L-S-X]-K-G-P-(D-1Nal)

Overview

NH2-c[X-R-L-S-X]-K-G-P-(D-1Nal) (compound 39) is a potent APJ agonist, with a K i of 0.6 nM. NH2-c[X-R-L-S-X]-K-G-P-(D-1Nal) can activate Gαi1 (EC 50 =0.8 nM) and recruit β-arrestin2 (EC 50 =31 nM). NH2-c[X-R-L-S-X]-K-G-P-(D-1Nal) exhibits prolonged cardiac effects.

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Apelin Receptor (APJ)

Product Information

• Catalog No.: HY-P3346
• CAS No.: 2891469-80-8
• Molecular Formula: C49H73N13O11
• Molecular Weight: 1020.18
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source