CD31 (PECAM-1) is platelet endothelial cell adhesion molecule-1, serves as the endothelial cell-specific receptor of clostridium perfringens b-Toxin ( CPB ). CD31 is also an ER-MP12 antigen , acts as a linker between mechanical stress, metabolism and inflammation. CD31 peptide is able to sustain phosphorylation of the CD31 ITIM 686 and of SHP2 and to inhibit TCR -induced T-cell activation - .
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