Barucainide

Overview

Barucainide is an Ib-class anti-arrhythmic agent (moderately blocking sodium channel ). Barucainide exhibits concentration-dependent inhibitory effects on the maximum upstroke velocity (V max ) of Purkinje fibers and ventricular muscle in dogs. Barucainide significantly shortens the action potential duration (APD). Barucainide significantly inhibits the pacemaker activity frequency of atrial tissue in rabbits and the enhanced automaticity of Purkinje fibers under normal resting potential in response to isoproterenol. Barucainide cannot inhibit the abnormal automaticity emission frequency of canine Purkinje fibers induced by barium. Barucainide can be used for research on arrhythmias.

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Heart Disease | Products > Disease Areas > Arrhythmias | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Sodium Channel

Product Information

• Catalog No.: HY-106718
• CAS No.: 79784-22-8
• Molecular Formula: C22H30N2O2
• Molecular Weight: 354.49
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source