Synstatin (92-119)

Overview

Synstatin (92-119) is an inhibitor of αvβ3/αvβ5 integrins and IGF1R with anti-angiogenic, anti-proliferative, antioxidant and anti-tumor activities. Synstatin (92-119) competitively blocks the capture of αvβ3 / αvβ5 integrins and IGF1R by syndecan-1, disrupts the formation of the syndecan-1 : integrin : IGF1R ternary complex, inhibits integrin activation and talin-mediated signaling pathways, and blocks VEGF -induced angiogenesis. Synstatin (92-119) is applicable to research related to cancer and hepatocellular carcinoma.

Application

Products | Products > Peptides | Products > Disease Areas > Cancer | Products > Signaling Pathways > Cytoskeleton | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Integrin

Product Information

• Catalog No.: HY-P5133
• CAS No.: 1259384-47-8
• Molecular Formula: C133H207N35O46
• Molecular Weight: 3032.27
• Purity: 97.61%
• Storage: Sealed storage, away from moisture and light. Powder -80°C, 2 years , -20°C, 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
• Availability: In-stock

Source

Original product source