Hyaluronan-IN-1

Overview

Hyaluronan-IN-1 (Pep-1) is a Hyaluronan inhibitor with a K d value of 1.65 μM. Hyaluronan-IN-1 blocks CD44 -dependent cell adhesion. Hyaluronan-IN-1 inhibits cell adhesion to hyaluronan substrates. Hyaluronan-IN-1 suppresses the development of contact hypersensitivity in mice by blocking the homing process of inflammatory cells to the skin. Hyaluronan-IN-1 also inhibits responses during the sensitization phase. Hyaluronan-IN-1 reduces lung metastasis of melanoma and prolongs the survival of mice. Hyaluronan-IN-1 can be used in research related to contact hypersensitivity, chronic skin inflammation, and melanoma.

Application

Products | Products > Peptides | Products > Disease Areas > Cancer | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Melanoma | Products > Disease Areas > Allergy | Products > Disease Areas > Cancer Immunology | Products > Disease Areas > Immunotherapy for Melanoma | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Signaling Pathways > CD44

Product Information

• Catalog No.: HY-P5352
• CAS No.: 299157-43-0
• Molecular Formula: C64H94N20O16
• Molecular Weight: 1399.56
• Purity: 99.84%
• Storage: Sealed storage, away from moisture. Powder -80°C, 2 years , -20°C, 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Availability: In-stock

Source

Original product source