LEAP-2

Overview

LEAP-2 (Human liver expressed antimicrobial peptide-2) is a GHS-R1a antagonist, with an IC 50 of 6.0 nM. LEAP-2 suppresses the orexigenic effect of ghrelin. LEAP-2 attenuates ghrelin-induced growth hormone (GH) release and reduces basal food intake. LEAP-2 exhibits antimicrobial activity against microbial model organisms. LEAP-2 can be used for the study of obesity and infection .

Application

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Product Information

• Catalog No.: HY-P5645
• CAS No.: 1683582-94-6
• Molecular Formula: C191H316N64O57S5
• Molecular Weight: 4581.27
• Purity: 98.55%
• Storage: Sealed storage, away from moisture. Powder -80°C, 2 years , -20°C, 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 2.5 mg/mL (0.55 mM); Clear solution
• Availability: In-stock

Source

Original product source