OPC-4392 is a orally active presynaptic dopamine autoreceptor agonist and postsynaptic D2 receptor antagonist. OPC 4392 reverses the Reserpine ( HY-N0480 )-induced dopamine accumulation, inhibits Apomorphine ( HY-12723 )-induced stereotypic and climbing behaviors in mouse models. OPC-4392 can be used as antipsychotic agent.
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