ZINC110492

Overview

ZINC110492 is a selective ligand of CS-ΔEx4 (a splicing isoform of citrate synthase (CS)) . ZINC110492 does not bind to CS full-length (CS-FL). ZINC110492 inhibits colorectal cancer (CRC) cell growth in cells overexpressing CS-ΔEx4 with an IC 50 of 7.840 µM. ZINC110492 significantly decreases both citrate and 2-hydroxyglutarate (2-HG) levels in the CS-ΔEx4-overexpressing SW1116 cells.

Application

Products | Products > Signaling Pathways > Others | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Biochemical Assay Reagents

Product Information

• Catalog No.: HY-Q51222
• CAS No.: 100264-64-0
• Molecular Formula: C20H12N2O4
• Molecular Weight: 344.32
• Purity: 90.0%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source