Indole-4-carboxaldehyde

Overview

Indole-4-carboxaldehyde is an ergot alkaloid precursor. Indole-4-carboxaldehyde attenuates the methylglyoxal (MGO)-induced expression of inflammatory-related genes, such asTNF-α and IFN-γ by activating NF-κB without toxicity in HepG2 cells. Indole-4-carboxaldehyde reduces the MGO-induced AGE formation and the expression of the receptor for AGE (RAGE). Indole-4-carboxaldehyde can be used for the study of hepatic steatosis.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Lipid Metabolism | Products > Disease Areas > Fatty Liver Disease | Products > Signaling Pathways > NF-κB | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > NF-κB

Product Information

• Catalog No.: HY-W001288
• CAS No.: 1074-86-8
• Molecular Formula: C9H7NO
• Molecular Weight: 145.16
• Purity: 99.32%
• Storage: 4°C, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
• Availability: In-stock

Source

Original product source