DMPX

Overview

DMPX (3,7-Dimethyl-1-propargylxanthine) is a selective A 2A adenosine receptor ( A 2A AR ) antagonist that crosses the blood-brain barrier, with a K i of 11 μM for rat A 2 adenosine receptor and a K i of 45 μM for rat A 1 adenosine receptor . By blocking A2A receptors in specific brain regions, DMPX protects dopaminergic and GABAergic neurons from mitochondrial dysfunction. DMPX is applicable to research related to depression, Parkinson's disease and Huntington's disease.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Neurodegenerative Disease | Products > Disease Areas > Depression | Products > Disease Areas > Parkinson's Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Adenosine Receptor

Product Information

• Catalog No.: HY-W004425
• CAS No.: 14114-46-6
• Molecular Formula: C10H10N4O2
• Molecular Weight: 218.21
• Purity: 99.66%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 4 mg/mL (18.33 mM); Clear solution
• Availability: In-stock

Source

Original product source