All-trans-retinal

Overview

All-trans-retinal is an vitamin A metabolite in the retina, and is produced following photo-isomerization of the visual chromophore 11-cis-Retinal. All-trans-retinal is cleared from photoreceptors by ATP-binding cassette transporter (ABCA4) and all-trans-retinol dehydrogenase (RDH). All-trans-retinal induces Bax activation via DNA damage to mediate retinal cell apoptosis .

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Endogenous Metabolite | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-W004500
• CAS No.: 116-31-4
• Molecular Formula: C20H28O
• Molecular Weight: 284.44
• Purity: 99.56%
• Storage: -20°C, protect from light, stored under nitrogen * The compound is unstable in solutions, freshly prepared is recommended.
• Solubility: ≥ 2.08 mg/mL (7.31 mM); Clear solution
• Availability: In-stock

Source

Original product source