Peldesine

Overview

Peldesine (BCX 34) is a potent, competitive, reversible and orally active purine nucleoside phosphorylase (PNP) inhibitor with IC 50 s of 36 nM, 5 nM, and 32 nM for human, rat, and mouse red blood cell (RBC) PNP , respectively. Peldesine is also a T-cell proliferation inhibitor with an IC 50 of 800 nM. Peldesine has the potential for cutaneous T-cell lymphoma, psoriasis and HIV infection research.

Application

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Product Information

• Catalog No.: HY-106934
• CAS No.: 133432-71-0
• Molecular Formula: C12H11N5O
• Molecular Weight: 241.25
• Purity: 99.98%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 5 mg/mL (20.73 mM); Clear solution
• Availability: In-stock

Source

Original product source