Mazapertine is an orally active antipsychotic agent. M azapertine antagonizes to dopamine D2/3/4 receptors ( K i values < 3 nM) and also strongly binds to serotonin 5-HT1A receptor ( K i =1.7 nM) and α1-adrenergic receptor ( K i = 1.3 nM). Mazapertine can be used for the research of neurological disease .
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