1-Aminoindan (1-Indanamine) is a Rasagiline ( HY-14605A ) metabolite. 1-aminoindan is shown to bind directly to α-Syn , thereby promoting a neuroprotective “loop” conformation that attenuates the α-Syn misfolding and aggregation. 1-Aminoindan is shown to be neuroprotective. 1-Aminoindan can be used in the research of Parkinson's disease.
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