SCH-42354

Overview

SCH-42354 is a potent, orally active neutral endopeptidase (NEP) inhibitor, is the pharmacologically active form of the proagent SCH-42495. SCH-42354 inhibits the hydrolysis of NEP to enhance the activity of atrial natriuretic peptide (ANP). SCH-42354 inhibits hydrolysis of leu-enkephalin and ANF with IC 50 values of 8.3 nM and 10.0 nM, respectively. SCH-42354 has antihypertensive activity.

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Neprilysin

Product Information

• Catalog No.: HY-106975
• CAS No.: 144505-58-8
• Molecular Formula: C16H23NO3S2
• Molecular Weight: 341.49
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source