2(5H)-Furanone

Overview

2(5H)-Furanone (γ-Crotonolactone) is an endogenous metabolite . 2(5H)-Furanone mimics N-acyl homoserine lactone signals, occupies the binding site of LuxR homologs, and interferes with quorum sensing-mediated gene regulation. 2(5H)-Furanone inhibits quorum sensing mediated by AHLs with different acyl chain lengths. 2(5H)-Furanone inhibits biofilm formation of environmental Aeromonas hydrophila strains on polystyrene plates. 2(5H)-Furanone suppresses spike-and-wave discharges in a rat model of generalized absence seizures and exhibits selective activity against absence seizures. 2(5H)-Furanone can be used in studies related to bacteria infections and generalized absence seizures.

Application

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Product Information

• Catalog No.: HY-W008270
• CAS No.: 497-23-4
• Molecular Formula: C4H4O2
• Molecular Weight: 84.07
• Purity: 99.94%
• Storage: Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (29.74 mM); Clear solution
• Availability: In-stock

Source

Original product source