N-Deschlorobenzoyl indomethacin

Overview

N-Deschlorobenzoyl indomethacin (Compound 18), the primary metabolite of indomethacin ( HY-14397 ), lacks the N-p-chlorobenzoyl group in its structure. Consequently, N-Deschlorobenzoyl indomethacin loses inhibitory activity against AKR1C2 and AKR1C3 ( AKR1C2 IC 50 =100 μM, AKR1C3 IC 50 >100 μM), exhibiting no selectivity.

Application

Products | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Others | Products > Signaling Pathways > Drug Metabolite

Product Information

• Catalog No.: HY-W008567
• CAS No.: 2882-15-7
• Molecular Formula: C12H13NO3
• Molecular Weight: 219.24
• Purity: 95.0%
• Storage: Store at room temperature 3 years. In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.5 mg/mL (11.40 mM); Clear solution
• Availability: In-stock

Source

Original product source