Amotosalen hydrochloride

Overview

Amotosalen hydrochloride (S-59) is a light-activated, DNA-, RNA-crosslinking psoralen compound, which is used to neutralise pathogens. Light-activated Amotosalen binds and permanently crosslinks DNA, preventing replication and thus stopping proliferation of donor T cells. Amotosalen can be used for the study of blood system pathogen reduction technology and graft-versus-host disease (GVHD).

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > DNA/RNA Synthesis | Products > Signaling Pathways > Parasite

Product Information

• Catalog No.: HY-107004A
• CAS No.: 161262-45-9
• Molecular Formula: C17H20ClNO4
• Molecular Weight: 337.80
• Purity: 99.86%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 0.71 mg/mL (2.10 mM); Clear solution
• Availability: In-stock

Source

Original product source