BMS-341400 mesylate is a selective phosphodiesterase 5 ( PDE5 ) inhibitor with an IC 50 value of 0.3 nM. BMS-341400 mesylate reduces the degradation of cyclic guanosine monophosphate ( cGMP ), thereby enhancing nitric oxide (NO)-mediated relaxation of the smooth muscle of the corpus cavernosum and promoting erection. BMS-341400 mesylate can be used to study erectile dysfunction.
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Phosphodiesterase (PDE)
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