Thiomichler's ketone (4,4'-Bis (dimethylamino) thiobenzophenone) is a heavy metal complexing agent and a colorimetric/spectrophotometric reagent. Thiomichler's ketone shows selectivity for Hg 2+ at pH 3, and exhibits activity towards Pd 2+ and Ag + at pH 3.5. Thiomichler's ketone enables accurate detection of trace Pd 2+ by forming an extractable Hg 2+ complex via micelle-mediated cloud point extraction, or generating a red coordination complex including Pd (TMK) 4 . Thiomichler's ketone is applicable for the determination of trace Pd 2+ in antibiotics and catalysts of automobile exhaust purifiers.
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