5'-Deoxy-5-fluorocytidine

Overview

5'-Deoxy-5-fluorocytidine (5-Fluoro-5'-deoxycytidine) is a cytidine analog and metabolite of Capecitabine ( HY-B0016 ). 5'-Deoxy-5-fluorocytidine is converted from Capecitabine by carboxylesterase in the liver. 5'-Deoxy-5-fluorocytidine is deaminated by cytidine deaminase to generate 5'-deoxy-5-fluorouridine, which is finally converted into 5-fluorouracil ( HY-90006 ) by thymidine phosphorylase in tumor tissues to exert anti-tumor effects. 5'-Deoxy-5-fluorocytidine is used in the researches for solid tumors such as colorectal cancer , non-small cell lung cancer and breast cancer .

Application

Products | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Drug Resistance | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Nucleoside Antimetabolite/Analog | Products > Signaling Pathways > DNA/RNA Synthesis | Products > Signaling Pathways > Drug Metabolite

Product Information

• Catalog No.: HY-W009538
• CAS No.: 66335-38-4
• Molecular Formula: C9H12FN3O4
• Molecular Weight: 245.21
• Purity: 99.91%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: ≥ 2.5 mg/mL (10.20 mM); Clear solution
• Availability: In-stock

Source

Original product source