AA 344 is an orally active antiallergic agent. AA 344 inhibits the IgE , IgGa, Concanavalin A ( HY-P2149 ), Dextran -mediated release of histamine. AA 344 shows inhibitory effects on the homologous passive cutaneous anaphylaxis and the passive systemic anaphylaxis in guinea pigs. AA 344 selectively suppresses the type I allergic reaction.
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