H-Ala-Ala-OH

Overview

H-Ala-Ala-OH is a substrate of human intestinal oligopeptide transporter ( PEPT1 /SLC15A1), with an IC 50 of 0.25 mM and an EC 50 of 0.08 mM against human PEPT1 . When used as a dipeptide linker in antibody-drug conjugates (ADCs) loaded with glucocorticoid receptor regulator payloads, H-Ala-Ala-OH enables efficient intracellular payload release.

Application

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Product Information

• Catalog No.: HY-W010162
• CAS No.: 1948-31-8
• Molecular Formula: C6H12N2O3
• Molecular Weight: 160.17
• Purity: 98.0%
• Storage: 4°C, protect from light, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
• Availability: In-stock

Source

Original product source