Methyl succinate

Overview

Methyl succinate is a mitochondrial complex II substrate. Methyl succinate can bypass the inhibition of complex I by Metformin ( HY-B0627 ), restore mitochondrial electron transfer, and reduce AMPK phosphorylation. Methyl succinate is capable of protecting MIN6 β-cells and primary rat β-cells from biguanide-induced toxicity and apoptosis in vitro. Methyl succinate can be used in the research of diseases such as diabetes mellitus.

Application

Products | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > AMPK | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-W010380
• CAS No.: 3878-55-5
• Molecular Formula: C5H8O4
• Molecular Weight: 132.11
• Purity: 99.94%
• Storage: Store at room temperature 3 years. In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.5 mg/mL (18.92 mM); Clear solution
• Availability: In-stock

Source

Original product source