Ampreloxetine hydrochloride

Overview

Ampreloxetine (TD-9855) hydrochloride is an orally active and CNS-penetrant inhibitor of Norepinephrine transporter (NET) and Serotonin 5-HT uptake transporter (SERT), but not Dopamine transporter (DAT). Ampreloxetine hydrochloride binds norepinephrine transporters (NET) and serotonin transporters (SERT) with EC 50 values of 11.7 ng/mL and 50.8 ng/mL, respectively, in plasma.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Depression | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Serotonin Transporter

Product Information

• Catalog No.: HY-107128
• CAS No.: 1227056-87-2
• Molecular Formula: C18H19ClF3NO
• Molecular Weight: 357.80
• Purity: 99.43%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Availability: In-stock

Source

Original product source