Pamoic acid disodium

Overview

Pamoic acid disodium is a potent GPR35 agonist with an EC 50 value of 79 nM. Pamoic acid disodium induces GPR35 internalization and activates ERK1/2 with EC 50 values of 22 nM and 65 nM, respectively. Pamoic acid disodium potently recruits β-arrestin2 to GPR35 and has an antinociceptive effect.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Depression | Products > Disease Areas > Pain | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > Stem Cell/Wnt | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > GPR35 | Products > Signaling Pathways > ERK

Product Information

• Catalog No.: HY-W010907
• CAS No.: 6640-22-8
• Molecular Formula: C23H14Na2O6
• Molecular Weight: 432.33
• Purity: 99.86%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 7.5 mg/mL (17.35 mM); Clear solution
• Availability: In-stock

Source

Original product source