Norfluoxetine-d 5 hydrochloride

Overview

Norfluoxetine-d5 hydrochloride is the d 5 -labeled Norfluoxetine hydrochloride ( HY-W011235 ). Norfluoxetine hydrochloride is the active metabolite of the antidepressant Fluoxetine ( HY-B0102 ); it is also a TREK-2 K 2 P potassium channel inhibitor . Norfluoxetine hydrochloride exhibits neuroimmunological activity, induces apoptosis in primary microglial cells, and inhibits the release of pro-inflammatory factors. Norfluoxetine hydrochloride inhibits high-threshold voltage-gated Ca 2+ currents in neurons with an EC 50 of 20.4 μM. Norfluoxetine hydrochloride can be used in research related to depression, ischemic stroke, and epilepsy.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Cerebrovascular Disease | Products > Disease Areas > Depression | Products > Disease Areas > Epilepsy | Products > Disease Areas > Ischemic Stroke | Products > Signaling Pathways > Others | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Neurological Disease | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Calcium Channel | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Isotope-Labeled Compounds | Products > Signaling Pathways > Drug Metabolite | Products > Signaling Pathways > Potassium Channel

Product Information

• Catalog No.: HY-W011235S
• CAS No.: 1188265-34-0
• Molecular Formula: C16H12D5ClF3NO
• Molecular Weight: 336.79
• Purity: 99.30%
• Storage: 4°C, sealed storage, away from moisture and light * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
• Availability: In-stock

Source

Original product source