2-Hydroxyanthraquinone

Overview

2-Hydroxyanthraquinone is a product generated by the photochemical oxidation of Anthracene (ANT) (HY-Y0299). 2-Hydroxyanthraquinone induces ferroptosis in cardiomyocytes by depleting GSH and inhibiting GPX4 , leading to cardiac developmental malformations. 2-Hydroxyanthraquinone causes damage to the cerebrovascular system and blood-brain barrier in zebrafish by downregulating the Wnt/β-catenin signaling pathway, as well as inducing inflammation and neuronal apoptosis . 2-Hydroxyanthraquinone can be used in studies related to cerebrovascular diseases and cardiotoxicity.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Cerebrovascular Disease | Products > Disease Areas > Cardiovascular Disease | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Stem Cell/Wnt | Products > Research Areas > Neurological Disease | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Glutathione Peroxidase | Products > Signaling Pathways > Ferroptosis | Products > Signaling Pathways > Wnt | Products > Signaling Pathways > β-catenin | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-W012352
• CAS No.: 605-32-3
• Molecular Formula: C14H8O3
• Molecular Weight: 224.22
• Purity: 98.0%
• Storage: 4°C, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
• Solubility: ≥ 2.5 mg/mL (11.15 mM); Clear solution
• Availability: In-stock

Source

Original product source