3,3-Dimethyl-1-butanol (DMB) is an orally active inhibitor of trimethylamine ( TMA ) and trimethylamine N-oxide ( TMAO ). 3,3-Dimethyl-1-butanol inhibits the signaling pathway of p65 NF-κB and TGF-β1/Smad3 . 3,3-Dimethyl-1-butanol has potential applications in cardiovascular disease (CVD).
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