Alpidem (Standard)

Overview

Alpidem (Standard) is the analytical standard of Alpidem ( HY-W013150 ). This product is intended for research and analytical applications. Alpidem , an anxiolytic agent, is an orally active and brain-penetrant GABAA receptor ligand, binds to α1β2γ2 subunit-containing GABAA receptors (IC 50 of 17 nM) over α5β2γ2 subunit-containing GABAA receptors (IC 50 of >10 μM). Alpidem modulates calcium-induced mitochondrial permeability transition, induces glutathione depletion and hepatocyte necrosis, potentiates TNF-α toxicity, inhibits marble-burying and locomotor activity, enhances stressed rodent feeding behavior, and exerts anticonvulsant effects. Alpidem can be used for the research of anxiety, anxiety disorders, and convulsions.

Application

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Product Information

• Catalog No.: HY-W013150R
• CAS No.: 82626-01-5
• Molecular Formula: C21H23Cl2N3O
• Molecular Weight: 404.34
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source