GI-530159

Overview

GI-530159 is a selective opener of TREK1 and TREK2 potassium channels. GI-530159 displays selectivity for TREK1/2 over TRAAK, TASK3 and other potassium channels, with an EC 50 of 0.76 μM for TREK1 . GI-530159 reduces rat dorsal root ganglion neuron excitability and shows potential analgesic effect.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Potassium Channel

Product Information

• Catalog No.: HY-W013712
• CAS No.: 69563-88-8
• Molecular Formula: C27H20F6N2O2
• Molecular Weight: 518.45
• Purity: 99.45%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 5 mg/mL (9.64 mM); Clear solution
• Availability: In-stock

Source

Original product source