N-Isovaleroylglycine

Overview

N-Isovaleroylglycine is a peptidylglycine α-amidating monooxygenase ( PAM ) inhibitor with a K i value of 2.0 mM against human hsPAM . N-Isovaleroylglycine undergoes oxidative cleavage by purified rat PAM to produce fatty acid amide and glyoxylic acid. N-Isovaleroylglycine exerts competitive inhibition by binding to hsPAM, blocking the amidation of dansyl-Tyr-Val-Gly. N-Isovaleroylglycine exhibits lowered urinary abundance in MRSA-infected mice, which qualifies it as a non-invasive biomarker. N-Isovaleroylglycine can be used in studies related to Staphylococcus aureus pneumonia and diabetic foot.

Application

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Product Information

• Catalog No.: HY-W015464
• CAS No.: 16284-60-9
• Molecular Formula: C7H13NO3
• Molecular Weight: 159.18
• Purity: 99.86%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (15.71 mM); Clear solution
• Availability: In-stock

Source

Original product source